Release of Envelope Glycoprotein from Rabies Virions by a Nonionic Detergent

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Release of envelope glycoprotein from rabies virions by a nonionic detergent.

Treatment of rabies virus with the nonionic detergent Nonidet P-40 resulted in solubilization of viral lipids and in a preferential release of the envelope glycoprotein. The other viral proteins and the viral ribonucleic acid remained associated in "core" particles sedimenting at a rate similar to that of intact virions. After fractionation of treated virus by velocity centrifugation in a sucro...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1971

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.8.5.649-655.1971